I missed this post by you about the gradient and septal thickness. My gradient before my first dose of Camzyos (5 mg) was 59.12, and 49.17 with valsalva. The gradient after 2 months on Camzyos was 11.89, and 11.15 with valsalva. There was no change in gradient when the dose changed to 10 mg and then back to 5 mg., but I was only on the 10 mg dose for a week or less because I notified my MD of worsening symptoms. I cannot find the figure for the septal thickness on the echo report (or more likely I don't know exactly what I am looking for or how to read it!) Obviously, the Camzyos has definitely helped me. I wish I had all or mostly all good days, but I still have one or two low energy days with shortness of breath per week. I am hoping the longer I am on the Camzyos, the better that will get. We shall see. Just fyi, I was not diagnosed until age 77, but at this point in my life my arthritis keeps me from doing many of the sports I enjoyed for so many years anyway. Please keep me posted on your progress.