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Has anyone had experience with Jakafi?
Blood Cancers & Disorders | Last Active: May 11 6:47pm | Replies (74)Comment receiving replies
I’ve had Polycythemia Vera for 14 yrs, then RBC went up, I was prescribed taking 1000mg of Hydroxyurea extra per week . I take 1000mg/day. Then everything fell to dangerously low counts . I went off the HU and waited 2 months for WBC to come up to the high end of normal. A new Dr has started me on Jakafi. 20mg twice a day for a month, then check blood levels. Has anyone taken Jakafi? How did it go?
Replies to "I’ve had Polycythemia Vera for 14 yrs, then RBC went up, I was prescribed taking 1000mg..."
Hi - I took jakifi for 10 months before my stem cell transplant for chronic eosinophilic leukemia. It worked great and I had no side effects or problems with my blood counts. The only reason I came off and did the transplant is because it tends to only work for a year or so for CEL and my doctors recommended doing the transplant sooner than later. Good luck.
After taking Hydrox. (500mg) for 2.5 years for PV, my PLT levels weren't coming down enough so my new Hematologist prescribed Jakafi instead. My PLTs shot way up so back to only Hydrox. but up to 1000mg a day. No bad side effects with either. Some drugs work for some, others not so much.
I was on HU for several years slowly upping dose. Then became in tolerant and all values crashed (lost >30lb in a month). Switched to Jakafi 10 mg 2x/day. I have ET, platelets still run above normal, all other are now in range. I've never had any issues with Jakafi and been on it 2+ years
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I have been on Jakafi for several years now. My hemoglobin dropped when I started the drug, but it wasn’t dangerously low. I stayed on it and my bloodwork stabilized over time. Jakafi does a great job controlling my GVHD. My doctor is now slowly decreasing the amount I take.