Sluggish thyroid…take or boost Liothyroxine
Really struggling with fatigue and depression, especially after a workout…usually so bad I can’t get out of bed the next day. I have depression, ADHD and Hashimotos. I take Prozac, Adderall, Levothyroxine and Liothyroxine. I just read that sometimes a sluggish Thyroid can make you treatment resistant and taking more Liothyroxine can help. Anyone else try this? If so, did it work? Also, I have a double mutation on DIO2 CC (Decreased conversion from T4 to T3) so I figure that is one of my many problems.
Interested in more discussions like this? Go to the Autoimmune Diseases Support Group.
@lgrec Welcome to Mayo Clinic Connect! We’re all volunteers who share information about health conditions. We can’t diagnose or tell you what you should do; only how we were diagnosed and treated. It’s a great group of people as I’m sure you will quickly learn!
@lgrec
Have you had recent TSH, T3, T4 and TPO bloodwork? How are your levels now on medication? Are you hypothyroid due to your Hashimoto’s and have you had an ultrasound of your thyroid recently to check for nodules?
Have you had your cortisol levels checked via 4 point saliva test?
It sounds like you may need a tweak on your medication or added. I was originally only taking Synthroid 112 mcg and I still needed more, so my doctor added 5 mcg’s of Cytomel and that put me where I needed to be for a while, then it was too much, causing body tremors, so went off Cytomel. I now am only taking 75 mcg’s of Synthroid for my hypothyroidism and I also suffer from Hashimoto’s. Due to having Hashimoto’s, I eliminated eating gluten, dairy and soy from my diet and have lost a lot of bloat in my body. I would see your doctor and have labs run again as you may need more medication. Good luck!
Can you see your provider for an exam blood work?
What test did you Dr do to figure out the problem with converting T4 to T3. I have the same issue. I have no T3 but since I started taking Cytomel and it has elevated my T3 to the middle range of normal.
Have the doctor check your iodine levels and correct this levels are off. Susan
Before increasing the thyroid meds dose, check iron levels and entire water /fat soluble vitamins/minerals/amino acids panel including iodine the 24 urine test (not from blood). You can be low in Vit D, or Zink is common as well. (You levels should be near the top of the reference)
Antioxidants like resveratrol, Quercetin, Q10 (+vit c) and others for ATP production /Mito works miracle.
Nicotinamide riboside is better than just niacin try Cell Guard - NR.
ADB5 Plus (Biotics) include adrenal gland if further boost is needed.
I discovered I have genetic folate and vit d mutation so had to change the form which helped as well.
On top of that try fasting and eat 1 time per day in 8 hours window. I put on continues glucose monitor and noticed that I am becoming fatigue after the snack or meal (basically when my sugar rises - insulin resistance). So switching to ketones as my primarily fuel of energy helped my brain.
I also went off Cytomel because it was too strong and switched to NTD (Thyroid NP). It works more soft and doesn't cause tremor or heart rate rises.
Are you seeing an Endocrinologist? You should be. The human hormones are a very delicate balance and adjusting then, even fine tuning requires indepth knowledge. Please see an Endo and ask the same questions. I would never try to pretend that the questions you asked have simple answers. They maybe simple questions, but that in no way says the answers are simple. It took over three years to initially balance my thyroid meds. Hang in there.