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Anyone have granulomatosis with polyangiitis (GPA) or Wegener's?

Autoimmune Diseases | Last Active: Dec 30, 2025 | Replies (63)
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I tried Rituximab last year and although it didn't work well for me, I remember getting a horse dose of prednisone (about 100mg if I recall correctly) right beforehand to lessen the chances of a reaction and then the Rituxan was infused very slowly over 6 hours. I didn't have any issues with it during or after the infusion. Maybe the protocols have changed since you last had it?

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Becky, Volunteer Mentor | @becsbuddy | Mar 28, 2025

@pm56 I’m sorry that it didn’t work so well for you. I don’t think there were any changes in the protocol, but I’d have to ask . Was last year’s dose the only one you received? I have received 3 doses so far, and each time i just pray like that it will work!
What other options has your doctor brought up?

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