I'm 66 and 2 months into a 6 month trial on ADT - Lupron Depot. The biggest issues i've had are occassional headaches, hot flashes (they suck), feeling weaker but I'm trying to offset that with working out, and the most troubling side effect for me is how much my testicles have shrunk. But since I'm only on this trial for 6 months I'm hoping that eventually my T levels will recover close to normal.

I haven't had any depression issues but I'm the kind of person that either pushes that down or I tell myself "stop being such a pu$$y" and I grind through the occassional down feeling. So far i havent felt "down" very much and i do try to surround myself with family and friends and keep myself occupied - the times i do get the occassional "down" feeling is when I'm alone and i try to avoid that.

For me, ADT is not as bad as some of the materials I read but it's def not optimal and you can expect some side effects. If, at some point, they tell me i have to go on ADT for YEARS, thats going to be a tough decision but if its between dying and having no T I'll prob choose no T.

Getting old isnt for the weak and one of my fav quotes from a Zach Bryan song is "In life having the upper hand's a myth, your only fighting chance is too stubborn to quit." I live by that credo - be too STUBBORN to quit, say F U to cancer, and power through it! You can do it !!!!