I know of other people who have had spikes in their PSA while on Pluvicto. Usually by the 3rd session the results will improve. Pluvicto works very well with 1/3 of patients OK with 1/3 of patients and not at all with 1/3 of patients. Some people have to stop because it doesn’t work or the side effects are too strong. It is probably worth at least 2 more session, but you should speak to your doctor and see what he/she has to say. I have never heard of the PSA going that high so that concerns me and I’m not a doctor.

My Chemo was deemed to have failed after 2 treatments of stagnate 13 PSA and I was allowed Pluvicto 12/2023. My PSA was halved with my next test. PSA dropped with each test after finally reaching 0.11-0.15 for the next months until 12/2024 when it began to increase. December was 1.05 followed by March 4.01. Pluvicto was a respite for me, I got to be myself again for 1 year or so. Side affects were minimal during the 6 treatments and for me was a blessing. Now I'm seeking another treatment plan, Oncologist appointment today. I was diagnosed in 2016 and am 74 now.