Hi Diane, Not much change in my numbness in the past 4 years but I do consider that a win since it's also not any worse. I do think the supplements I take help some but don't really make it go away which we all would like. I also think it's important to keep the skin hydrated with a good moisturizer. I like the LifeFlo magnesium lotion which seems to have a calming affect. The reason it's harder for me to tell if the numbness is any better is that I also have to wear 20-30 mmhg compression socks up over the calves and I always have that squeezing feeling on the feet and legs.

I've found it helps me walk a little better if I don't have the really cushy shoes that I used to love so much. I have some zero drop (flat) shoes that help me feel the ground a little better but if I have to walk any distance like to a Mayo appointment in downtown Rochester, I like a little cushion to make the walk easier.

I asked about Metanx at one point in time but was worried about the B6 content as a lot of research points to causing neuropathy (B6 toxicity) if the levels are too high. @ray666 started a discussion awhile back on EB-N5 which may be another option - https://connect.mayoclinic.org/discussion/eb-n5-and-idiopathic-pn-long-term-usage/.

I would keep asking questions and learning about any new treatments that may be available. It pays to advocate for ourselves. Hoping you find some answers! John