When I switched from Lupron to Orgovyx My hot flashes actually stopped completely for about four months. Then they started coming back to about the same level that I had with Lupron. Definitely did not get any worse with orgovyx.

I have the same thought. With very high risk disease, the slower recovery time for testosterone might not be a negative in terms of time to BCR. While the side effects of lupron + abiraterone + prednisone were present for the 2 years I was on it (plus a good part of the following year), I wouldn't hesitate to use lupron again, if needed. I recently looked back through the gallery of pictures on my phone. Those two years were spent kayaking, hiking, xc skiing and mountain biking with family and friends. We also put in a large veggie garden at the cabin. And yes, there were far more naps than usual, but they kept me going. It did take longer than usual to complete some projects, such as painting the exterior of the house, but it made me realize that there was no particular reason that I had to complete it as quickly as I normally would have. PCa has made me slow down, find the good in each day ( even the tough ones), and appreciate life, one moment at a time, a great deal more than I used to.
Bill

On my fifth day with ADT Orgovyx. No hot flash (yet), hope it won't be a problem for me.
For those who experienced hot flashes, after how many days or weekd on this medications did your first hot flash occur?