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Is PSA rise inevitable after hormone therapy?

Prostate Cancer | Last Active: 3 days ago | Replies (45)
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@heavyphil

A quick Google and the answer is Docetaxel, which is already extensively used in triplet therapy or alone after ADT failure.
Many on the forum have used this drug and reported success; also, the fearsome side effects of “chemo” seemed to be felt to a lesser degree by most patients.
Having not gotten to that stage myself ( hopefully NEVER🤞) I was not familiar with the taxane family of drugs, sorry…

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Replies to "A quick Google and the answer is Docetaxel, which is already extensively used in triplet therapy..."
northoftheborder | @northoftheborder | Mar 23 4:38pm

Yes, the triplet of chemotherapy + ARSI (like one of the -lutamides) + ADT (like Orgovyx) seems to be the cutting-edge standard of care for polymetastatic prostate cancer these days.

For oligometastatic, spot radiation to the individual metastases seems to be preferred over chemo, but I'm sure there are many exceptions.

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