My T is low normal but my Estradiol is very low which could be causing some of the symptoms I'm having. Apparently, both are necessary. My medical oncologist does a FULL testosterone workup that includes Sex Hormone Binding Globulin, Estradiol, Luteinizing Hormone, Prolactin, Testosterone Total and Testosterone Free.

Testosterone was decent last time but has dropped instead of going up. It's still in the low normal range (barely). Estradiol is abnormal at 4. Luteinizing Hormone is off the charts high at 18 (9 should be the max) which mean my pituitary gland is telling my body to make more testosterone and estrogen but my body isn't listening so it's cranking up the volume. I think the doctor talking about a patch means a very low dose, not a testosterone-depleting dose but need to clarify that with him since it does sound unconventional (which is probably why the radonc is not recommending it).

I was feeling OK but have started feeling crappy again with a lot of the side effects I had on ADT (insomnia, moodiness, hip and back pain, depression, tiredness, etc.) even though I've been off it almost six months and all the Orgovyx should be long gone. Dr. Google says all this could be a sign of testicular failure but my doctor says not to jump to that conclusion just yet.

The only good thing is my PSA dropped again to .04 but I just want to feel like myself again.

@heavyphil Misread your comment about Wearing an estradiol patch which reduces testosterone just as well as ADT. Sorry

One of the groups I Attend has a GU oncologist come to the second meeting every month. He publishes a newsletter and covered the patch study, which is done in Europe, so there hasn’t been as much information here in the USA.