← Return to Gleason 8 diagnosis at 51: Likely opting for surgery

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@brianjarvis

With your Gleason 8, was that a 4+4, 3+5, or a 5+3?
Any cribriform pattern, PNI, SVI, ECE, or other concerns?
When you mention PSMA being negative, what does that mean - nothing seen even in the prostate?
What were your genetic (germline) test results?
What are the many factors you’re using in deciding on treatment type?

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Replies to "With your Gleason 8, was that a 4+4, 3+5, or a 5+3? Any cribriform pattern, PNI,..."

Ismging was all negative. The overread noted some pni in a 3+3 core. Overall, I am 4+4.

I accidentally hit the reply button.

What is germline? My decipher was 0.2.

The PSMA report said negative in prostate, but my oncologist said that it lit up just not enough to determine cancer. Not sure what to make of that, but it is a little concerning.

For treatment, my main concern with RT plus brachy boost plus ADT is the risk of viable cancer cells being left in the prostate. I am aware thst durgery carries a high risk of SRT.