1. < Osteoporosis & Bone Health

Positive Evenity results

Posted by neesie0159 @neesie0159, Jul 23, 2024

I had my DEXA scan a week ago after finishing Evenity just over a month ago. With my luck I was expecting little results. Luckily it was good! Lumbar spine went from -4.6 to -3.0 Right femoral neck from -2.9 to -2.2. All the ridiculous copays were worth it to have my spine improve that much. My new PCP (I moved 3 months ago) hadn’t gotten the report as of today, so I downloaded it from my patient portal and emailed it to her. I still have a crappy spine, but not nearly as crappy as it was. Just a tip, be persistent when you need something medical. The place I was originally referred to for the DEXA said they couldn’t get me in until mid August. Multiple calls later, I got an appointment elsewhere within a few days. When I hadn’t heard from my PCP a week after the scan I called them. I don’t know what’s next yet, rheumatologist was pushing Prolia partly because it’s once every 6 months instead of a daily pill, but I had no unmanageable side effects with alendronate and Prolia is an unknown. Thanks for reading!

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

bktexas | @bktexas | 14 hours ago
In reply to @nemorose "greetings, All! May IO suggest a wonderful natural product - a liquid silica - called ORGONO..." + (show)
@nemorose

greetings, All! May IO suggest a wonderful natural product - a liquid silica - called ORGONO SILIPLANT - my nails are super strong, and my hair (I'm 80) is long and thick - I do color it!!! Having a hard time giving that up, for sure. You can take as many servings as you like, but it's an incredible product, and I have a number of friends who also swear by it. I take one - two servings a day. It comes with a plastic measuring cap.

Jump to this post

Hi, why are you having to give it up?

REPLY
ashash | @ashash | 3 hours ago
In reply to @gently "daisy17, do you remember where you read that Evenity doesn't provide much protection against fracture. Outside..." + (show)
@gently

daisy17, do you remember where you read that Evenity doesn't provide much protection against fracture. Outside of the other cautions, I'm wondering about the bone--the quality of the bone. My understanding is that it is modeled bone rather than remodeled. Meaning that it doesn't allow for clearing away old bone, simply lays down new bone on top of the old. Sort of like replastering or repainting your house without removing the broken, damaged material underneath. In cartoons showing the bone laid down, there isn't any articulation. It is just solid bone. And easy to see why bone mineral density would be increased without reduction of fracture risk. I don't know, but it makes me wonder.

Jump to this post

I have exactly the same question.
After finishing 12 Evenity injections, I had a DEXA to see what had changed--same machine, no changes in its calibration or software, same technician. DEXA showed all areas returned to osteopenia range, and the prescribing endo complimented the treatment, saying I was no longer in osteoporosis.
I then went to a REMS provider, and had a scan there. Results show that I am still in the "red zone" for fracture in both femoral necks, hips in general.
I asked the test technician, a PhD in pharmacology, the same question you just asked.
He replied that he could never understand the logic behind Eventiy-->Reclast, for the very reason you bring up.

REPLY
deborahla | @deborahla | 1 hour ago
In reply to @daisy17 "I am also curious about the quality of the bone produced by Evenity, for two reasons:..." + (show)
@daisy17

I am also curious about the quality of the bone produced by Evenity, for two reasons: 1. You must take another drug, like a bisphosphonate, after Evenity or you lose all your gains. I am curious as to why? That doesn't sound like typical bone to me. I've tried to research this on-line but can't find anything about this. 2. I've read that Evenity doesn't provide much protection against vertebral fractures which makes me wonder if taking the drug is worth the risk of the side effects. (I am in the U.S.).

Jump to this post

I am not sure if this addresses your question exactly but it is my understanding that : Postmenopausal women experience a shift in bone remodeling, with bone removal (resorption) outpacing bone building (formation) due to the significant drop in estrogen levels following menopause. So after you stop the Evenity your bones are not forming bone as usual before menopause (the bones are experiencing removal of bone) so I think that is why you need another drug to lock in the gains (or prevent his breaking down).

I have read different things on the internet about protection against vertebral fractures. It appears it does protect somewhat but has to be followed up with other drugs.

I would say that whether the drug is worth the risk of side effects would depend on your particular situation. For me it was as I felt it was the best treatment for me right now. I have taken 2 injections without any side effects, age 71, T score was -3.7. I am still considering what I will use after I finish the 12 month course of Evenity.

REPLY
View MoreView Less
Please sign in or register to post a reply.