Connect
Discussion
Comment receiving replies
Replies to "Hi, in this video, it is not clear what new drug or treatment this Doctor is..."
Blood Cancers & Disorders | Last Active: 5 hours ago | Replies (143)
Comment receiving replies
Hi, in this video, it is not clear what new drug or treatment this Doctor is referring to, which he says attempts to make Myelofibrosis regress, instead of just masking tge symptoms. Please say. Thanks. THURS, 13 March
Replies to "Hi, in this video, it is not clear what new drug or treatment this Doctor is..."
Connect
Hi @bmarkable. I believe the medication Dr. Tefferi was talking about in the video is Imetelstat.
People with MF or other myeloproliferative neoplasms have an elevated telomerase activity. This drug, Imetelstat (Rytelo) is a telomerase inhibitor.
Two articles for you to read if you’re interested.
From Pub Med:
https://pubmed.ncbi.nlm.nih.gov/35510486/
From BloodCancersToday.com:
https://www.bloodcancerstoday.com/post/impactmf-ongoing-assessment-of-telomerase-inhibitor-for-relapsed-or-refractory-myelofibrosis
What treatments are you currently receiving for your MF?