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Anyone want to talk about Myelofibrosis?

Blood Cancers & Disorders | Last Active: Apr 12 8:47am | Replies (166)

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@bmarkable

Hi, in this video, it is not clear what new drug or treatment this Doctor is referring to, which he says attempts to make Myelofibrosis regress, instead of just masking tge symptoms. Please say. Thanks. THURS, 13 March

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Replies to "Hi, in this video, it is not clear what new drug or treatment this Doctor is..."

Hi @bmarkable. I believe the medication Dr. Tefferi was talking about in the video is Imetelstat.
People with MF or other myeloproliferative neoplasms have an elevated telomerase activity. This drug, Imetelstat (Rytelo) is a telomerase inhibitor.

Two articles for you to read if you’re interested.
From Pub Med:
https://pubmed.ncbi.nlm.nih.gov/35510486/
From BloodCancersToday.com:
https://www.bloodcancerstoday.com/post/impactmf-ongoing-assessment-of-telomerase-inhibitor-for-relapsed-or-refractory-myelofibrosis
What treatments are you currently receiving for your MF?