For MGUS there are no symptoms. Calcium levels will be elevated but that is usually when bone lesions start or CRAB symptoms start which means MM which you do not have. Rarely does MGUS evolve into SMM. Then rarely does SMM evolve to MM. it’s usually a slow process. Having abnormal M proteins and/or elevated immunoglobulins is the first indication of MGUS. A baseline has been documented. Now future lab results will be compared to this in determining progression or stability. I have SMM. It has been stable for a year. I’m older at 67 and how I deal with my anxiety is knowing that I will be under a doctors care in dealing with this for the rest of my life. Nothing will slip thru the cracks. Clinical trials are also available. Living an active life is my main stay. I would be lying if I said it’s not always on my mind. But therapy and meds are helping me cope.