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@colleenyoung

Hi @ceri, using search you'll find a few discussions, mostly in the Osteoporosis group where members have talked about the estradiol patch. See search results here:
https://connect.mayoclinic.org/search/?search=estradiol%20patch
Ceri, are you concerned about HRT in relation to Leiden Factor V or other blood disorder?

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Replies to "Hi @ceri, using search you'll find a few discussions, mostly in the Osteoporosis group where members..."

Hi @colleenyoung

Yes, I am concerned about HRT in relation to Factor V Leiden. I have heard that the estradiol patch is possibly safe, but I'm not sure how accurate that is. I have Factor V and my doctor prescribed the estradiol patch, but I’m concerned about using it.