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@ronegeorge

Hydroxyurea tends to lower blood cells, so it's unlikely to help with low platelets. JAK inhibitors may help with that. Myelofibrosis can present with either hyperproduction of blood cells or hypoproduction, for unknown reasons; basic to both presentations is that the blood cells are not being produced properly for what the body needs. Ron

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Replies to "Hydroxyurea tends to lower blood cells, so it's unlikely to help with low platelets. JAK inhibitors..."

My platelets recently went up to over 1200 due to a drug trial I was on. They took me off of that and increased my hydria which I have been on since 2021 to four pills a day, from 2. The side effects I've had from hydrea before this taking a thousand milligrams a day was my taste buds. I've gotten to the point where nothing taste good and it's hard to eat resulting in weight loss. My doctor says that Hydra will work to lower platelets. It's only been a couple of weeks so we'll see what happens.
I'm having severe symptoms of the higher platelets, dizziness, double vision, arm and leg weakness, numbness in lips and tongue. Very scary.