Hi arecchie, I was diagnosed with ET (Jak2 mutation) in November 2022. Started with 500 mg Hydroxuria daily. Unfortunately it did not lower my platelets. My number was 763 initially. Only went down a little bit. After 4 months I started taking 1000 mg daily, lowered platelets to 365. I get checked every 4 months. My platelets went up to around 400 in the last 2 1/2 years. O/H is not concerned. All other numbers are good. Still on same dosage, once in a while I have a mouth score, my Hair thinned out a little bit. Just started taking Biotin. Not sure if it will help. Other than that I have no side affects. I am almost 70 years old. Had some thinning hair before taking Hydroxuria. It is not bad at all, hoping for the best.
Best wishes to all of you
Regina