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Kevzara

Polymyalgia Rheumatica (PMR) | Last Active: 1 hour ago | Replies (73)

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@wellsbjt

I have had a similar experience with Kevzara. I felt almost normal in a few days. I was also able to taper prednisone from 13 mg to 5 mg in less than 6 weeks. However, after the latest reduction to 5 mg this week, I am having sweats, headaches, nausea and fatigue. Although I have only been on steroids a few months, I guess the discomfort may be caused by my adrenal system trying to wake up. My question: what did your taper schedule look like once you reached 5 mg. ? Did you have to alter it from your earlier schedule?

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Replies to "I have had a similar experience with Kevzara. I felt almost normal in a few days...."

I've had to tinker and tweak the tapering ever since I dropped below 10 mg. And 5 mg was a real threshold into a new level of difficulty. I seem to need, and my Dr who is a rabid dog about getting me off Prednisone as long as I can function reasonably well while doing it, realizes that there is a need to allow time to destabilize at the new starting dose, whatever it is that I'm returning to - usually 5 mg. The last drops to 4 then 3 went surprisingly well. My personal lessons are: 1. Toggling between doses (like 5 mg and 4 mg) is helpful for a few days. 2. The 5 to 4 and 4 to 3 drops both seemed, in hindsight, to need a first trial that fails, then a pause at the higher dose for 3 weeks then a successful drop. 3. The 4 to 3 drop benefitted from my first effort with .5 mg doses - I dropped 4 to 3.5 mg for 3 days, felt the mounting symptoms and did a single day at 4 then BOOM dropped to 3 and didn't have any symptoms at all. I can only guess that my adrenal need a little bit of gentle jiggling and poking and shaking to cajole them into working harder.