Day 21 on Fluorouracil cream. I was instructed to use from chest up to forehead for 21 days. After 14 days of agony burning on my chin, I stopped using on my chin, but continued on chest, neck, cheeks and forehead through day 15 & 16. I've gone through the gamut, burning, bleeding, scabbing even woke this morning with a scab on my upper lip which immediately came off and bled. My doctor gave me a choice, she said " if you don't want to use it, then go ahead and take the chance of getting melanoma". I don't consider that a choice! This has been excruciatingly painful and on top of that I've had many obligations and been out nearly everyday amongst people looking like a monster. I was told no makeup. I couldn't put make up on this cracked. bleeding, peeling, burning skin if I wanted to! Day 8 was my last shower....too painful. I can barely even wash my face or chest with all the raw, bleeding sores. I truly don't know if I've got the constitution to do this again and I'm positive my doc will want me to every year or two. I pray that nobody else has this much agony with this treatment. I can't stress enough to take precautions outdoors when you young. I doubt anyone living has been burned over my lifetime, I'm 67, more than I. I'm medium complexion & have had a deep, dark beautiful tan every summer since I was 13. Everyone compliments me on my tan. I'm finally beginning to wonder if it has been worth it. Yes, that's just how much I love tanning! I understand people have questioned my sanity! Now I'm questioning it myself!!!