@susanjohnston, I can't say my endocrinologist has been very helpful in giving advice. I sent some messages through my portal to him with some questions about the fact that my blood calcium levels are typically on the higher side of normal, and having tests done before I started Tymlos, and he pretty much blew me off. He wants to see me in a year, which I think is ridiculous. Taking a powerful drug like Tymlos, I would have at least hoped he'd want to check my blood levels in 6 months!

Anyhow, the people on this site have helped much more than the doctor and nurse, who was very rude when I asked her questions about how to do the injections. So I listened to @windyshores and @gently and drink a couple glasses of water before hand and eat something salty before hand as well, and I believe that has helped. My blood pressure is normally low, so I am used to eating salty stuff during the day, even though I know salt is not good for you. In my case, I seem to need it. I have had hyponatremia multiple times, and once ended up in the hospital almost in a coma from it, so I am used to eating salty stuff whenever I feel symptoms starting, or see that my blood pressure is lower than my normal.

The rapid heartbeat is also something I am used to, so I don't worry about it, as it is short-lived. But I think I read on this site that someone said elevating the feet above the heart helps. I have an adjustable bed, so I have been elevating my feet for about 20 minutes after the shot and that does help.

Hope that helps.