Dear Lilly71,
I have tried everything out there on the market, and saw a neurologist at the Barrow Institute in Phoenix three years ago. The Barrow is a large and respectable neurological think-tank to help people with RLS in the Parkinsons Center. He placed me on premipexole, which today, is the wrong thing to administer, due to the symptoms become worse, as augmentation occurs. Then he suggested a "drug holiday" the worst thing in the world: you slowly diminish the pramipexole with no other drug aid to get over the hump; then nothing! I was up a night for hours. I ended my relationship with him, and saw another neurologist with Banner Movement Disorder, recommended by the neurosurgeon who placed a spinal cord stimulator in my spine for what I believed could help the pain and RLS. Unfortunately, it didn't help, and I am having it removed next month, after two years. This doctor placed me on methadone, and the panic attacks were scary. Possibly in time, the SCS or a type of device implanted with help with RLS. It is when I received a referral to the sleep specialist at Mayo, who after interviewing me and truly listened I had PLMD, another form of RLS, and treated me with a small speck of buprenorphine. The dose is quite small, .66 mg of a 2 mg tablet. I am so against drugs, and was so worried about augmentation, but after almost one year, it has enabled me to sleep, and travel in a car or an airplane without the leg jerks. Please do not give up, see about the buprenorphine.