How many of our Fathers had BPH Prostate issues or Prostate Cancer

My father died of prostate cancer at 88. His father probably had undiagnosed BPH and died at 98. My brother and I both got PC. I got it at 62 and had BRCA2 from my mother. My Brother got it at 76.

I know a number of other people that have the same situation. I know two sets of three brothers who all have prostate cancer and no genetic issues.

My father had a few bouts back in the day with probable prostatitis or BPH; he died at 72, however, from mesothelioma.
But my maternal grandfather died from metastatic prostate cancer at age 67, but his son (my uncle) died at 80 from Parkinsons and never had prostate issues at all; neither of his daughters (my mother and aunt) ever had breast/ovarian cancer and lived long lives, so I don’t think there’s a genetic link from them to me cancer wise.
But I think BRCA mutations can skip a generation so maybe? I’ve gotten the genetic testing kit recommended by jeffmarc but just as I was about to spit into the tube, my mouth became unusually dry. Decided to put off any insights into my corrupted DNA for another day😉

Several of my uncles had prostate cancer. All of my cousins on my father’s side had prostate cancer. I became aware of this when I was diagnosed with prostate cancer. I also learned about how Agent Orange exposure likely caused my cancer. It has been interesting to learn all of this. I have two sons I’m concerned about and will help them monitor their health.

My Dad was diagnosed with prostate cancer at age 70. They decided on an active surveillance strategy (I think they called it "watchful waiting" then). Things worked out as expected - he died ten years later of congestive heart failure.

jeffMar . It certainly did not shorten anyones lifespan . KEEP UP THE RECORD .

My dad was only male of his family and had PC diagnosed around age 72 then had Orchiectomy at age 75. Must have worked as he died at age 93.
My brother has PC and RALP at age 67 and is clear so far (12 years). My mom's family didn't disclose any PC but they weren't known to be very open about medical issues.
I've hounded my two sons to keep a check on their PSA and they do now.

BRCA can’t actually skip generations, but getting no cancer with it sure can, the point I think you were trying to make. If my mother didn’t have BRCA I could not get it. But her father sure had it when he died of pancreatic cancer in his 40s. The interesting thing is my mother‘s two sisters both got breast cancer, one of them died from it, And one of the daughters died of breast cancer, But my mother never had any cancers.

I am 49% Ashkenazi, The highest risk for BRCA, It is sort of weird since my father is Swiss Italian and my other half of DNA is all from there. The 49% that I have was after five generations of family in the same city, Which means four generations had to all be Ashkenazi for me to have that high a percentage.

Prromise, who does the free genetic test, Sent out a graph showing the personal hereditary information of people that took the test.. That’s how I knew what my percentages were. One benefit of taking the test is you’ll get that as well It did take them a couple years between taking the test and sending that information.

Dad at 61, me at 60. My father lived to 82 and did not die of PCa. Back in the day (2000), it was remove everything if you had surgery - RP with no sparing of nerve bundles and orchiectomy. I am considering the orchiectomy route too and plan to better inform myself on the topic and discuss with urologist.

Not sure about my dad but my brother had pc around the same time I did and he went on to have pancreatic cancer. My Uncle also had pancreatic cancer. It’s hard to fully understand the confusing cancer waves related to genetics but all we can do is stay vigilant.

Those cancers are all related to having the BRCA genetic Defect. Have you had your hereditary genetics checked? The reason you want to do this is, if your children also have it they are warned about possible cancers.

If you live in the USA, you can get your Hereditary, genetic test for free from the below link. Don’t say that you want your doctor involved or they won’t send you the kit until they speak to your doctor. A geneticist will contact you about the results.

Prostatecancerpromise.org