What is minimum period of Alendronate to minimise Prolia rebound?

Posted by surefire @surefire, Jan 14, 2024

I started on Prolia in July 2022 on advice from my doctor that the treatment would be for only 4-5 years and thereafter I could stop. I have taken 3 Prolia injections, the last one in July 2023.

Before my 4th injection in Jan 2024, I started doing a lot of reading and decided that I do not want to be on any osteoporosis drug at all. So, instead of taking my 4th Prolia injection and to minimise the rebound effect from stopping Prolia, I started on a weekly dose of Alendronate.

However, I am really not comfortable taking Alendronate as well and would like to seek any advice/opinion on whether I am stuck with taking Alendronate for the next 6, 12 or even 24 months.

What is the shortest period I can be on Alendronate? Or should I just risk the rebound effect and stop my Alendronate now (I have taken 3 weekly doses so far)?

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hmbrglr | @hmbrglr | 3 days ago

I am fairly new here and I am at the same exact spot where you were when you asked this question. I am curious as to what your decision was and where you are at in this stage. I am in good physical shape and exercise daily for 1 hour or more. I would like to stop as well . I would like to know how you are doing.