Can I quit Prolia shots after taking five shots without problems?

I totally agree with you that Prolia is a serious med, and all decisions need to be made in partnership with your doctor. The 5 to 6 number that I remember is from the clinical studies that were presented in Santa Fe earlier this year – – But certainly, I am no expert, And I had hoped that my comments were taken in that light. I hopes that each person can find a great doctor. They feel good about and make their decisions accordingly.

I stopped Prolia after about 6 shots and went on Boniva monthly, exercising, eating healthy etc. After a little over a year I have had 3 new compression fractures of the spine and my bones are very fragile. I am 67 years old! The rebound effect of stopping Prolia can be devastating so make sure you have a good plan for transitioning . I know now my PCP was not knowledgeable enough about the risks of stopping Prolia. You basically need to plan to be on it the rest of your life if you start.
I started Tymlos 4 days ago and I am praying it helps me build back some of the bone I have lost and I can go forward from here much more informed.
So many of us are just flying blind, trusting our medical professionals to lead us in the right direction….
This forum has been so helpful to me!

@jennirdf McCormick told me that Boniva is not a good choice among the bisphosphonates to manage rebound, and after 6 shots would recommend Reclast. I have several fractures and extend my sympathies! MCCormick in "Great Bones" and Leder in his video on You Tube (Combining and Sequential Approaches to Osteoporosis) say that Tymlos and Forteo are not effective after Prolia but since you did a bisphosphonate in between, I am hoping you get good results. Maybe you can do Evenity after the Tymlos as well.

Thank you for your input, @windyshores. I do not have GERD. I just recently had two fractures that were due to falls so my numbers would have been the same. I also believe that Fosamax would not be strong enough. My endocrinologist has recommended Reclast and my rheumatologist just went along with the suggestion. Neither of them mentioned any concern about side effects.
It's shocking to me how quickly and easily the physicians prescribed meds without fully explaining the pros and cons. I guess it is up to us to educate ourselves.
When I look back at my records, I do not think that my numbers were ever low enough to require meds. I wish that I had done more research and tried to work on improving my bone health naturally.

Everyone is different of course but I had a serious rebound effect after going off Prolia within 15 months, even w a biphosphonate directly following. Do plenty of research and maybe get a second and third opinion, you do not want to have happen to you what some of us are going through. It was never explained to me either the trauma of what the rebound could do to me. I am (was) and otherwise healthy, active, fit 67 yo
Who right now feels like a bent over old lady, trying desperately to get some vitality back. One of the main things I am working on is forgiving myself for not asking more questions and researching. But I am trying to look forward now, and just get better!

How many injections did you have? Had you had previous fractures?

I am experiencing the same feeling as you. I feel so stupid not asking questions when l was prescribed prolia. Dr did not give me any information.

Of course Evenity is made by the same company as Prolia, AMGEN. How clever to produce a drug which you cannot stop and then come up with another drug. No wonder they just floated on the American stock exchange. They have also bought up many global biotechnology factories.

May I ask why you stopped. Was it your decision or was your physician involved? It sounds risky to ... stopping without a plan to manage rebound.

Just an FYI.... I was on Prolia for two years and started Evenity. I just had my 12th Evenity shots. I had a DEXA the same day as my last shots. I gained 8% in my spine and had gains in hips and femurs as well. No fractures coming off Prolia. I was a -3.8 going into Evenity and now a -3.3. I am wondering what to do next since I am 71 and don't want to start Prolia again until all my other options are exhausted. Wish I could stay on Evenity for at least 6 more months. Is Forteo an option?

I had a fracture of L2 in 2016 when I was coughing badly with bronchitis. It amazes me that the dexas still show “osteopenia” for my diagnosis, even after 4 fractures! There is so much margin of error in the scans; the skill of the technician, the radiologist who reads them, I know for a fact from looking at my past results that sometimes the radiologist (different ones) has included a compressed vertebrae in the analysis which of course will read very DENSE and throw the whole thing off. That’s why I am now insisting on bone turnover marker labs every 3 months.
I had 5 injections of Prolia, so two and a half years of it. My physician never discussed with me the possibility of a rebound effect and put me on monthly Boniva. I wanted to stop bc I was wary of ALL injections and concerned that they would start using MRNA in them. I did not get the covid shots and was becoming distrustful of the direction the medical professionals were going, all corporate and pushing all vaccines on everyone, especially those who had natural immunity. That’s it in a nutshell. Of course the irony is that now I inject myself every day w Tymlos…
That’s a long answer but hopefully explains my thinking.