MGUS is considered asymptomatic and with a 1%/year risk of progressing to SMM or MM. However, there can be symptoms such as neuropathy in some people, especially if the MGUS proteins increase. I was diagnosed with MGUS 8 years as a follow up to my polyneuropathy diagnosis, but it also be part of celiac. Either way, the neuropathy is pretty minor in me. I collect autoimmune diseases so figuring out what causes what is like solving a puzzle.