I receive the Gem-Doce infusions while in a hospital bed at the infusion center. Those receiving systemic treatment are usually sitting up. I keep the bed flat the whole time. It seems to take the pressure off. In the past, patients were told to roll from side to side when receiving chemo or BCG to assure the entire bladder was touched by the infused agents. The American Association of Urologists has debunked this, stating it has no proven value. On the days of the first two infusions, I got up at 4:00 a.m. and drank 48 ounces of water and two 12 ounce cups of coffee. I then worked out for about 90 minutes. I was producing very little urine at the time of infusion; it made it easier to retain the chemo. Last time I had water up until four hours before. It was horrible.