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Effects of HRT: Alone, in Combination or Sequencing
Osteoporosis & Bone Health | Last Active: Feb 27 9:19am | Replies (86)Comment receiving replies
@mayblin…this is such good news. I am 72, had a complete hysterectomy in my late 30’s was on hormones for a short time and ended up with severe osteoporosis. Diagnosed in 2020, I then went on a 2-year protocol of Tymlos in 2022 and had great gains. My rheumatologist wanted me on Evenity to lock in my gains but I chose to try bioidentical hormones which my cardiologist suggested. After his unexpected death I was referred to a very proactive and progressive integrative obstetrician gynecologist who agreed that HRT would help my bones.
I’ve been on them since July and will meet with my obstetrician soon to see if the hormones are maintaining my bones. She has me on an estrogen patch, oral progesterone and a testosterone creme.
Did you go straight from ur Forteo protocol to HRT?
Your info is invaluable. Thanks for sharing. Rose
Replies to "@mayblin…this is such good news. I am 72, had a complete hysterectomy in my late 30’s..."
Hi @dooshie thank you for sharing your experiences and your inquiry. Yes, I went from Forteo directly to HRT (without testosterone). Coincidentally like you, I started HRT last July. Looks like it has held my bmd so far (per Jan 2025 DXA scan) and helped gaining more.
Looking forward to hearing your dexa results. It will be nice to get bone marker labs done to see if they correspond to dexa results.
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Hi, @dooshie: Would you mind letting me know what your cardiac issue is that your cardiologist suggested HRT instead of Evenity? I have a left branch bundle block and have variously (depending on the doctor) been diagnosed with cardiomyopathy; basically, my heart doesn't pump efficiently and it's now controlled by a pacemaker. My current cardiologist feels I'm not a heart attack risk and to rule out stroke risk he ordered a carotid study. I don't have results of that yet. But his opinion after googling Evenity was that it wouldn't be risky for me. He said the same about HRT. He has not studied either in depth, mind you, and he seems to be more concerned about the osteoporosis -- that I will break a hip and consequently die -- than he is about my cardiovascular risk.
My endocrinologist, meanwhile, disagrees both about the Evenity and the HRT risk. She has had two patients have a heart attack on Evenity, but they had no known cardiac problems, and as far as I'm concerned, might have been heart attack candidates without the drug. No way to know, right? As far as HRT goes, I am 73, more than 10 years past menopause, and because I've got a heart condition she thinks HRT is "too much risk for too little reward." She wants me to start Prolia and then go on Reclast.
I am VERY disappointed by her point of view, but it's given me enough pause not to trust my cardiologist's, either. So could you tell me why your cardiologist shied away from Evenity but felt HRT would be safe enough for you? It might help me to know given that both have cardiac risks.
Thanks for any words of wisdom... 🙂