Biopsy or not?

Posted by monteshark @monteshark, Jan 29 6:49pm

My PSA went from 2.2 to 2.3 over 5 years, which is nothing. I have chronic prostatitis and BPH. The velocity is very low

I’m 64 and in good health, no
Meds and physically active.

The VA ordered me to have a MRI with contrast. They rated my MRI at Bi-Rad 3. I had an MRI 5 years ago from a different source and they rated me Bi-Rad 2.

I’m arguing with myself to have a biopsy. Thoughts???

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@monteshark

Agreed on several fronts and thank you, my primary care Doctors want to do more imaging and follow my PSA. My urologist did a follow up urine bio test that was suspicious. On the basis of the urine test coming back Ww are doing the biopsy. My number 1 concern is failing to follow up, having something and it spread before we can kill it. I understand how slow prostate cancer is but a couple of friends have died from it. Many others have survived it. It’s crazy how many people I know have it. I think the odds are it’s nothing. I’m hoping for the best and expecting the worst. I’ve had so many past prostate problems I’ve kind of been waiting for this thing. I’ve had severe prostatitis, BPH with symptoms, and two infections since 52, I’m now 64 and in excellent health.

Thank you again

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@monteshark
I have had friends die of prostate cancer as well.

My Mayo urologist told me the same thing most others hear. "You will die of something else not prostate cancer." I did not like that as wanted my cancer treated.

I see many on MCC saying their cancer spread outside of prostate. Thus getting tested and treated as early as possible I think is major importance.

I was also told if a man lives long enough he will have prostate cancer. What I see a lot is the cancer is at cellular level not tumors. And what they see on Gleason Score is difference in normal cells from cancer cells.

That biopsy will give you a Gleason Score and that is really going to help you and your doctors know if you have it and if so treatment options.

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@jc76

@monteshark
I have had friends die of prostate cancer as well.

My Mayo urologist told me the same thing most others hear. "You will die of something else not prostate cancer." I did not like that as wanted my cancer treated.

I see many on MCC saying their cancer spread outside of prostate. Thus getting tested and treated as early as possible I think is major importance.

I was also told if a man lives long enough he will have prostate cancer. What I see a lot is the cancer is at cellular level not tumors. And what they see on Gleason Score is difference in normal cells from cancer cells.

That biopsy will give you a Gleason Score and that is really going to help you and your doctors know if you have it and if so treatment options.

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Everyone I know that has survived and thrived has cut this off at the pass. My uncle had his prostate removed in his early 60s. This was fine in the late 1970s. Techniques and treatments have changed drastically and improved. He was butchered and incontinent the remainder of his life. He died at 80 of a heart attack.

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Curious if you have any other testing to support a diagnosis and biopsy? Did you have a DRE and they found a lesion or a 4Kblood score, a psma pet scan?
I was diagnosed with a PSA of 3.2 (age normal), DRE found a tumor, 4Kblood score predicted 34% chance of fast-moving cancer, then a confirming mri with contrast, then a biopsy which was positive followed by PSMA Pet scan looking for spread prior to removal. Now doing salvage radiation and ADT 26 months later.

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All
I recently had an MRI with contrast which detected lump on prostrate but no lymph node or other areas showed up. The staff at Moffitt Cancer Center in Tampa scheduled me for MRI guided biopsy, but after doc reviewed my case which included recent rise in PSA from 1.4 to 4, the doc changed order to perform new urine test to determine if biopsy is really necesary. Here is link describling the new urine test:
https://prevention.cancer.gov/news-and-events/blog/improved-prostate-cancer-biomarker-test-may-help-men-avoid-unnecessary-biopsy
I received the urine test kit in mail and sent my sample off for testing and hope to hear results soon to possibly skip another biopsy. I just turned 80 last month and have previously survived esophageal cancel, kidney cancer, and thyroid cancer treatment at Moffitt.
Don

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Not heard of this test being widely used but you want to be doing a test like this to see if you really need a biopsy. The PSE Test is 94% accurate in figuring out whether you need to do a Biopsy. You send them a blood sample for this test.

The “my prostate score” 2.0 test you are just taking is only 52% accurate. Might mention that to your doctor and ask if maybe the PSE test would be possible.

Here’s a list of all the major tests With their Percentage accuracy

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@dsh33782

All
I recently had an MRI with contrast which detected lump on prostrate but no lymph node or other areas showed up. The staff at Moffitt Cancer Center in Tampa scheduled me for MRI guided biopsy, but after doc reviewed my case which included recent rise in PSA from 1.4 to 4, the doc changed order to perform new urine test to determine if biopsy is really necesary. Here is link describling the new urine test:
https://prevention.cancer.gov/news-and-events/blog/improved-prostate-cancer-biomarker-test-may-help-men-avoid-unnecessary-biopsy
I received the urine test kit in mail and sent my sample off for testing and hope to hear results soon to possibly skip another biopsy. I just turned 80 last month and have previously survived esophageal cancel, kidney cancer, and thyroid cancer treatment at Moffitt.
Don

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Wow, you’ve been blessed to survive all this. I lost my brother to esophagus C

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@chippydoo

Curious if you have any other testing to support a diagnosis and biopsy? Did you have a DRE and they found a lesion or a 4Kblood score, a psma pet scan?
I was diagnosed with a PSA of 3.2 (age normal), DRE found a tumor, 4Kblood score predicted 34% chance of fast-moving cancer, then a confirming mri with contrast, then a biopsy which was positive followed by PSMA Pet scan looking for spread prior to removal. Now doing salvage radiation and ADT 26 months later.

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My PSA has dropped to 1.87 now. I went in yesterday for a new PSA. My primary care ordered that. I’m now waiting for a focused biopsy, they can’t use my current MRI so they’re doing that again to conduct it. My DRE is negative the urine PSE test is slightly elevated

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