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Anyone have intermediate Macular Degeneration

Eye Conditions | Last Active: 3 days ago | Replies (75)

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@sjs1

I would be interested to know how many females are diagnosed with AMD are also on HRT. My MD wants me to take it for the first time at age 75 because of my intermediate dry AMD condition. He says
that estrogen is protective and surely I would not have this condition if I had been on HRT. He is a MD who just practices preventive medicine. He is not a retina doctor. He says it will help with the progression. I haven’t taken it so far because my other MDs take the conventional route. It is not conventionally advised to take low dose estrogen at 75. I think it’s important to know how to ask ChatGPT questions about the supplements other than ARED2 that are helpful. All the retina specialists are just going to give you the routine or conventional take: Take AREDS2 and wait, look at the amsler chart. I found out from “23 and me “ that I have the worst prognosis, thecdouble Y402H alleles in the CFH family from both parents but my AMD did not start in the fifties. My CFH DNA with these mutated alleles have the worst prognosis. I use the off label longevity drug rapa or sirolimus very low dose 5 mg with a MD’s prescription and supervision. It has been 8 to 10 years now still diagnosed with AMD and it’s at the intermediate dry. I use a low vision optometrist for driving glasses. I take more supplements than conventionally advised by a retina soecialist like Mitq foreyes, NMN, NAC, Melatonin etc all found from reading articles on intermediate dry AMD research and from the advice from a science website Admin who also has dry intermediate I haven't been to Wills, Wilmer or Duke, the top eye hospitals near me but I will visit each to introduce myself so tha when the clinical stems cell trials are more frequently conducted I might be considered given my DNA mutations. chstGPT gave me the names of the intermediate dry AMD studies currently underway and the MDs there who are the principle intermediate dry AMD researchers. I use the eyecharger device, a red led 670 hz flashlight used in the mornings for 3 min each eye to stimulate the mitochondria of which ChatGPT approves and this device is the result of the research if Dr Jeffrey at Univ of London neuroscience dept. Of course my retina doctor had never heard of eyecharger although photo modulation is now being researched and may be implemented in clinical settings for intermediate dry AMD. AMD is a disease of mitochondrial dysfunction. Most with AMD disease (like 50 percent) will have a DNA mutation component which causes mitochondrial dysfunction and disruption to the eye’s immune system in those who environmental factors are also present like having being a smoker —but hopefully not the worst scenario like mine. Research ChatGPT found research articles that report that my DNA mutations quickly progress to geographic atrophy. It’s very important to take AREDS2 and see a retina doctor 2x a year. There are subscription devices you can use that are a home monitoring device. You look into them daily and it reports back to monitoring station to gauge if your eyes have changed for the worse. I looked into it - didn't like the bureaucratic management. At my age and for the long time I have been in the intermediate stage I can’t just “wait and see “ for just the FDA approved modalities like those who can who are diagnosed in their fifties,

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Replies to "I would be interested to know how many females are diagnosed with AMD are also on..."

I am going to reply to everything soon. I do want to ask where you live, state? I've been to the John's Hopkins Wilmer eye institute last August. It is the opthalmologists there who told me I have decades before this will affect me. Now, my 2nd retina specialist says the same thing. I live in Maryland just outside of Baltimore. I would love to visit the Bascom Palmer Eye Institute in Miami Florida. I'm trying to work it out.
Also, the Photobiomodulation (red light therapy) was FDA approved in November 2024. My specialist is not getting a machine but he thinks Hopkins may. He says the results are not plentiful, for a lack of another word, for him to invest in at this time.
Also, were you ever diagnosed with early Macular Degeneration or have you only known for the 10 years of intermediate MD?

Also, I was reading about eye drops that may replace injections. My retina specialist has heard of them. I hope I remain mild, intermediate, and dry forever. Or at least long enough to benefit from some of the newer treatments headed our way.

I reread your above post regarding 23 and me. That one is a swab that is mailed away, correct?
You are 75, have had intermediate AMD for at least 10 years? And did not have it in your 50's. If you were diagnosed at 65 with intermediate AMD, how old were you when you were diagnosed with early stage AMD? Is 65 years old the age in which you became aware of the AMD for the first time? I'm just curious if you were getting regular dilated eye exams in your 50s and even younger.
I'm just trying to fit all of this new info into my brain and make sense of it.