I gained 3 lbs the next morning after my first shot. It took the whole month to lose 2 of the 3 lbs. The next shot I gained another 2.5 lbs and I gained 1 pounds after my third shot. I am currently up 2 lbs over my pre treatment weight. I walk an hour a day on the treadmill and get an average of 20,000 steps a day, I do resistance training and eat clean and healthy. This has been the most frustrating side effects from the injection.