Hello, I have dealt with histamine intolerance. It was discovered when I went to my dermatologist for itchy skin and what looked like a rash in a couple of places. As he looked over my skin, he noticed my thumb and asked to look at it. He said that was Green Thumb - an infection. The hives on my back and itchy skin was my body's way of alerting my system there is a problem. I thought I had a bruise on my thumb. He prescribed an antibiotic and a cream to calm my skin and hives. I also a functional medicine doctor (with a nutritionist on her staff) and she prescribed Hist Ease and D Hist - Natural D-Hist - "a targeted blend of flavonoids, antioxidants, proteolytic enzymes and botanicals designed to provide comprehensive support for seasonal challenges caused by common environmental allergens. The formula includes quercetin, bromelain, stinging nettles leaf, and N-acetyl cysteine." The nutritionist gave me a list of low histamine foods to concentrate on eating and eliminating the high histamine foods for a period of time. You can google both high histamine foods low histamine foods and get lists. I highly recommend you start with these lists and search for a functional medicine doctor or a naturopath or osteopath to help you. You can search for a functional medicine doctor by city and state at ifm.org. Best to you. You can get this under control and feel better.