I went to a GI doctor in Phoenix and she diagnosed globus just by talking to me about the symptoms and considering my age, 75 at the time. She prescribe Omeprazole(Prilosec) 40 mg twice a day. I could not tolerate that dose and after 2 weeks stopped taking it.

2 years later I went back to the same GI's office and the PA prescribed Omeprazole 20mg, delayed release, once daily upon waking in the morning. I tolerated this quite well. After 2, 30 day treatments, I felt better and it seemed like the Globus feeling was gone. Hope this helps.