Looking for help and support in stopping Effexor

Posted by magskay @magskay, Feb 4 7:56pm

I want to discontinue Effexor. I’ve heard horror stories. Looking for answers, solutions that worked. I’ve been on it for about 16 years and am down to lowest dose available. If I miss a dose I get terribly sick with dizziness and nausea. It’s awful.

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This is an eye opener for me. I know some antidepressants have unpleasant side effects. Most meds do. But to have withdrawals after taking this for a while seems to be contrary to the benefits of taking this med. I mean dealing with depression is hard but also dealing with Effexor withdrawal makes it even more difficult to manage your moods your health everything.

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@scarletb

I've been on all kinds of antidepressants in the last few decades and getting off Effexor is by far the most difficult. I'm back on it now because it seems to be the only thing that works (for awhile) and I'm trying not to dread the inevitable poop-out and discontinuation.

When I got to the lowest dose (37.5), I also couldn't just stop taking it without getting awful withdrawals. I bought some empty medication capsules and made my own lower-dose Effexor. At first I would open up an Effexor capsule and pour the contents into 2 empty capsules. Then, a few weeks later, I'd open up an Effexor capsule and split it 3 ways. Etc. I eyeballed it but I think I've read (maybe here?) about people using tweezers to count out the little pellets inside the capsules to be more precise.

The step from the lowest dose to zero is HUGE and unless people have experienced it, they really don't understand how awful it can be. At some point I will have to go off Effexor again and I'll use the empty capsule method for sure. Hope this helps!

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I am weighing the beads in the capsules with a mg scale I bought, then making new capsules with the smaller dose(mg). It's as accurate as I can be. It also preserves the extended release quality, as opposed to switching to immediate release and cutting pills.

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@msh466

This is an eye opener for me. I know some antidepressants have unpleasant side effects. Most meds do. But to have withdrawals after taking this for a while seems to be contrary to the benefits of taking this med. I mean dealing with depression is hard but also dealing with Effexor withdrawal makes it even more difficult to manage your moods your health everything.

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I agree. I’m not happy with the doctor who prescribed this. I would never advise anyone to take it. He said nothing to me about the nightmare of missing a dose or to getting off it.

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@mmsm

I am weighing the beads in the capsules with a mg scale I bought, then making new capsules with the smaller dose(mg). It's as accurate as I can be. It also preserves the extended release quality, as opposed to switching to immediate release and cutting pills.

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I hadn’t thought about the extended release aspect. Thanks for mentioning that.

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@magskay

I agree. I’m not happy with the doctor who prescribed this. I would never advise anyone to take it. He said nothing to me about the nightmare of missing a dose or to getting off it.

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It's been my observation since taking myself off of Efexxor and being on a few forums including this one that doctors generally don't inform patients about how difficult it is to quit taking. Pharmacists tell you not to stop taking it without consulting your doctor, but again, no discussion of how hard it is. I feel that this is wrong. According to ClinCalc, more than 2.8 million Americans are presently taking it (https://clincalc.com/DrugStats/Drugs/venlafaxine). How many are informed in advance? People go onto antidepressants for very real reasons, and some are desperate. Effexor is very effective for a lot of people. But they should be told. In too many cases, that's not happening.

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Doctors and pharmaceutical companies seem to have no accountability. That needs to change. Laws should be passed to insure patients are fully informed regarding any and all drugs prescribed.

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@magskay

I'd like to get off antidepressants completely. I believe there are more natural supplements such as 5 htp with no withdrawals or side effects. I would be willing to take another antidepressant in the process of weaning off Effexor, however.

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You can.
I take desvenlafaxine. I've had no withdrawals. It's been 50 days.

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@mmsm

You didn't taper down the effexor at all? No withdrawal?

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That's correct. I was stuck at the normal spot of 37mg. However, when I started the desvenlafaxine I also took 75 MG of venlafaxine for 3 days. Then stopped the effexor completely. It worked. I am now. On the 50mg of desvenlafaxine which I need. But when it's time to stop it, the step-down is much easier than stopping the effexor.

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@larrypains

That's correct. I was stuck at the normal spot of 37mg. However, when I started the desvenlafaxine I also took 75 MG of venlafaxine for 3 days. Then stopped the effexor completely. It worked. I am now. On the 50mg of desvenlafaxine which I need. But when it's time to stop it, the step-down is much easier than stopping the effexor.

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Wow, I'm surprised and envious all at the same time! Good for you!

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The way I got off 25 years of 150mg Effexor (venlafaxine) was:
Cold turkey. No! Had a long, terrible experience.
Started again at 75mg.
Once I had stabilised, bought a 4-weekly pill dispenser and a pack of empty capsules.
There are 6 little white pills inside a 75 mg venlafaxine SR capsule.
Set one pill aside for the first 10 days, leaving 5 little pills in each capsule, thus reducing from 6 to 5. (used the original capsule). Marked the dispenser on the day I reduced the dose. Very easy to forget.
Set two pills aside for the next 10 days, leaving 4 little pills in each capsule, thus reducing from 5 to 4. Marked dispenser on the day I reduced the dose.
Then set three pills aside for the next 10 days, leaving 3 little pills in each capsule. Marked the dispenser.
Then set four pills aside, leaving 2 pills and got a strong reaction. Google said, talk to your doctor, but he didn't have a clue. Fortunately a student doctor explained ratios and fractions in stepping down from 3 to 2, instead of the gap between 4 to 3, so I went back to 3 little pills for 10 days, and stabilised, followed by 2 1/2 for 10 days, then 2, then 1 1/2, then 1, then 1/2, (when I needed to use the empty capsules) then an approximation of 1/4, manipulated with eyebrow tweezers, followed by crumbs and kept on at that for a couple of weeks until I decided that this was silly, so I stopped. Clean!
I'm posting this because, back then, I really needed to know it was possible to stop, and found nothing. It is possible. I've done it.

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