1. < Osteoporosis & Bone Health

Tymlos vs. Evenity

Posted by eliz4142 @eliz4142, Mar 8, 2024

Hi all. I experienced a compression fracture at L1 about 4 weeks ago and this is how I learned I have osteoporosis. I'm "only" 57 and, after having a lot of blood work done, there is no explanation for my bone loss. I was adopted, so I don't have a lot of information about my genetics. Seems it's just an unusual (though not unheard of) situation. Since I've experienced a fracture already, my doctor has advised me that I need an anabolic agent. I'm trying to decide between 24 months of daily Tymlos or 12 monthly injections of Evenity. The doc assures me both are really effective. Evenity seems to have some serious (though unlikely) side effects, but definitely seems like a more palatable regimen. Any thoughts or experiences that might help me decide would be appreciated! Thank you!!

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osteoresearch | @osteoresearch | Feb 4 8:00am
In reply to @bktexas "Thx for your kind reply! Simply said, we just do not know. Have you had any..." + (show)
@bktexas

Thx for your kind reply! Simply said, we just do not know. Have you had any side effects from the Tymlos? My dr had said I might feel dizzy, so might have to sit or lay down for awhile.
If I may ask, was it your dr recommendation to start HRT along with the Tymlos? My dr didn't mention HRT at all.
By all means, wish you the very best with your treatment. I'd love to be kept in the loop!

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I do not have side effects with Tymlos. But b4 I inject each morning I drink a full glass of water with a pinch of mineral salt. Also I always move afterwards doing physical chores, or going for a walk. I do not think I wd feel good if I were to lay down. As for HRT-I chose that on my own to help combat any negative effects from Tymlos such as fatigue, wt. gain, etc. I also do weights and want to increase my chance of muscle building. When I look at my health history, ie: cancer and bone loss, these both occurred post estrogen loss so I decided to add that back in to help maintain and generally feel better. I take estradiol patch, progesterone pill at nite and testosterone cream. I will post any updates along my journey. I am hoping for any better alternative over bisphosphonates by the time I end Tymlos.

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