Do I have Cancer or Not?

Posted by theanomaly @theanomaly, 1 day ago

Age 48

Age 47 First PSA was normal January 2024 at 2.48. June 2024 it rose to 3.44 and January 29th 2025 it is 3.58.
June 2024 MRI PIRADS 4 and PIRADS 3 lesions
July 2024 Biopsy - 11 cores benign prostate tissue with chronic inflammation and atrophy. Core F . ***There is a focal region of Atypical glands 0.2mm suspicious for Adenocarcinoma. These cells lack basal cell markers and AMACR amber staining is not definitive.*** I was placed on 6 month active surveillance as Ive already gone through two biopsies looking for cancer cells. Doctor cannot declare me cancer positive or cancer negative. The diagnostic uncertainty is frustrating. Anyone else have a similar experience? Ive been told the lack of basal cells in the Atypical glands is a definite concern.

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@theanomaly

11 Cores are benign Core F is what worries me. Atypical Small Acinar Proliferation, suspicious for adenocarcinoma. These glands lack basal cell markers which is a serious red flag.

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Yes, that does seem to imply you do have cancer, but it can’t be seen by the tests. You could try getting a PSE test. They are 94% accurate in7 figuring out whether or not you have cancer from, a blood sample. Your doctor may know of another test like that. You don’t know right now and that may give you the ability to know. .

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@clandeboye1

@theanomonly , Sounds like you are naive about prostate cancer . ASAP go buy Dr. Patrick Walsh's book :
" Guide to Surviving Prostate Cancer " . Have you consulted with a 2nd Urologist at a Center of Excellence ?
Have youu had a 2nd or 3rd opinion of your biopsy results ? If not -- Do ASAP .
With Rads 4 there's a 80 % + chance, you have cancer .

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I'll definitely order it now, I had no idea a RADS 4 would mean an 80% risk of having cancer. Are there any charts that verify the percentages?

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