Key point from the link below:
Prednisone doesn't solve the problem!
https://www.pmrandil6.com/PMRPathophysiologyandIL-6Monograph.pdf
-------------------------------------------
"Studies have shown IL-6 levels are rapidly suppressed by corticosteroids, which are commonly used to manage PMR symptoms. However, plasma IL-6 levels
immediately increase upon short-term withdrawal of corticosteroids, despite several months of treatment, suggesting that corticosteroids do not correct the
underlying mechanism that causes elevated IL-6 levels in PMR."
--------------------------------------------
Furthermore, long term prednisone use compounds the problem after the side effects from long term prednisone use begin to materialize. Don't let anyone convince you that prednisone side effects are easy to manage when you know how. The worst side effect, in my opinion , is adrenal suppression which makes it nearly impossible to stop taking prednisone. Clearly there needs to be better treatment options to replace prednisone.

hi @dadcue are you still somewhere warm ?
That link is quite the literature review, isn't it ?
and like I said below, that entire webpage does look revised , and says on top "for US healthcare providers" . I notice that I can no longer access uptodate.com , can't get a password , things like that . I think that one is (now) truly limited to physicians . @seniormed do you know anything about that ?