Replies to I am JAG2 negative, CALR type 1 mutation positive found now, and I believe MPL negative.

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Essential Thrombocytosis symptoms

Blood Cancers & Disorders | Last Active: Nov 18, 2025 | Replies (172)

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@1pearl

I am JAG2 negative, CALR type 1 mutation positive found now, and I believe MPL negative.

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Replies to "I am JAG2 negative, CALR type 1 mutation positive found now, and I believe MPL negative."

nohrt4me (Jean) | @nohrt4me | Jan 30, 2025

Welcome to the CALR club. Me, too. Good news with CALR is that we don't have as many clotting incidents as people with JAK2. CALR patients also cannot progress to polycythemia vera.

But less is known about this mutation and how it affects overall health and longevity.

Hoping you can get some answers about the enlarged joints. Glad that is not painful for you.

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