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DiscussionAlternative treatment instead of Prolia injections
Osteoporosis & Bone Health | Last Active: Feb 4 10:23am | Replies (59)Comment receiving replies
Replies to "My endocrinologist suggested prolia almost two years ago. I have put her off because of the..."
@tik it's bisphosphonates like Reclast that are limited to 3-5 years. Prolia studies now go up to 10 years and may continue to extend duration.
I am surprised at the posts that indicate choices limited to anti-resorptives like bisphosphonates and Prolia. For any significant osteoporosis, anabolics like Forteo or Tymlos are good first drugs, or Evenity, which is both anabolic and anti-resorptive. Maybe recent posters have osteoporosis that is mild.
Anti-resorptives may affect the effectiveness of anabolics .
Reclast is prescribed after Prolia to manage rebound increase in fracture risk and loss of bone density.
McCormick ("Great Bones") and Ben Leder MD (YouTube videos) say that Tymlos and Forteo don't work well after Prolia. I am not sure if there is a period of time between Prolia and those meds that makes them effective again.