I was on Lupron for seven years before Orgovyx was available and then switched to Orgovyx for 1.5 years. I became castrate resistant. (PSA rising) after about four years, The same will happen to you at some point if you keep on Orgovyx for a lifetime.

After about eight years, my oncologist agreed to let me stop taking it. It isn’t likely my testosterone will come back much at all after that many years. If it does, I will have to go back on it. I am on Darolutamide And it’s working great as a single drug.