It gives me hope that maybe my platelets will settle down! I too am MPL driver, and have had my dosage of Hydroxyurea altered frequently, since my platelets are not responding so well. Right now I am still over 600, so my dosage was increased to 500*2 5 days a week and 500 on the weekend. Last time that the dosage was this high my white blood cells dropped so much that they had to reduce my dosage. Prior to this latest increase I had been 500*2 on the weekend and 500 mg the other 5
days. And prior to that it was 500 mg 7 days a week. (That was after my white blood cells dropped) Seems to be a real balancing act ….i hope we get it right soon.