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Can anyone tell me why I have an M spike every two years since 2019. Each time it gets higher . Not yet outlandish. At 3 now. When it is not there I am told I do not have MGUS anymore. Then 6 months later it is back at a higher level. I do not get it. I do have neuropathy but not bad. This all started with a fall and a fractured hip plus replacement last year. Could it be that now that the hip is back to normal it just goes away?
Thanks
Replies to "Can anyone tell me why I have an M spike every two years since 2019. Each..."
If your M spike is at 3 and you have neuropathy, you need to see a myeloma specialist at a center that sees a high volume of patients.
I have had MGUS since 2002. The M spike has varied from 1.1 to 1.7 and back down again. I think my hydration at the point of the blood draw may be responsible for the variation.
I also had a fractured hip that was replaced in January 2021. Surgery was done under regional anesthetic not general anesthesia. My free light chains went up and then came back down again. The M spike did not change. However, when I had a reverse shoulder replacement surgery in 2023 under a half hour of general anesthesia, my free light chains soared. They have decreased but not to the level they were before I had the surgery. I do not understand why as I had no problems with the surgery and feel great now.
My previous (now retired) hematologist wanted my bloods drawn every three months. The current one in the same practice thinks yearly is fine -- and every six months if I choose. I do choose every six months.
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Where are you monitored/treated? If it's not at Mayo, I would request to have the lab testing done at a different lab company.