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Evenity

Osteoporosis & Bone Health | Last Active: 1 day ago | Replies (53)

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@bayhorse

@windyshores, you are brave to have tried Evenity given your clotting risk. I don't know if I have your courage; will keep researching and checking the sources you mentioned, for which I am very grateful.

I have an implanted pacemaker/defibrillator, and in spite of the pacing, Tymlos frequently upped my heart rate. The palpitations didn't last long, but were quite noticeable!

I have one other question you might be able to address: The endo I saw last week told me that there is a 6-month window of stability after stopping Prolia before the high risk of fracture starts. I thought patients went high risk, especially for spinal fracture, immediately after quitting Prolia. Do you have any info on this?

Thanks again for any help you can give.

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Replies to "@windyshores, you are brave to have tried Evenity given your clotting risk. I don't know if..."

@bayhorse my lay person's reading of this https://pmc.ncbi.nlm.nih.gov/articles/PMC5915244/
is that yes meds to prevent rebound (bisphosphonates) should be started 6 months after the last Prolia shot. I would rely on your endo!

I think "immediately after stopping Prolia" would still mean 6 months after the last shot, since Prolia's action lasts that long. Again, sounds like you have a good endo.

I wasn't "brave" to try Evenity. I was satisfied that the study showing cardiovascular risk on Evenity being the same as placebo to be quite reassuring in that regard. That said, I had other concerns since sclerostin has functions throughout the body. But people are having truly amazing results.

Ineresting experience on Tymlos with a pacemaker!