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Essential Thrombocytosis symptoms
Blood Cancers & Disorders | Last Active: 2 hours ago | Replies (115)Comment receiving replies
But that's almost a 50% reduction, et1055!
Congratulations, especially since your initial count was so high.
For me (with the very stubborn MPL driver), it took 14 months of HU to get from the high 700s to 505.
I'm grateful my oncologist considers 505 acceptable, and that his incremental dosing meant no side effects from HU.
Replies to "But that's almost a 50% reduction, et1055! Congratulations, especially since your initial count was so high...."
It gives me hope that maybe my platelets will settle down! I too am MPL driver, and have had my dosage of Hydroxyurea altered frequently, since my platelets are not responding so well. Right now I am still over 600, so my dosage was increased to 500*2 5 days a week and 500 on the weekend. Last time that the dosage was this high my white blood cells dropped so much that they had to reduce my dosage. Prior to this latest increase I had been 500*2 on the weekend and 500 mg the other 5
days. And prior to that it was 500 mg 7 days a week. (That was after my white blood cells dropped) Seems to be a real balancing act ….i hope we get it right soon.
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My oncologist is also happy with my numbers in the 500s and uses incremental dosing too. I was at 800 two years ago; now in the 500s. Overall, blood work big picture is better. I take baby aspirin in the AM and PM, 500 mg of HU 4x a week, and a daily iron supplement due to low iron but not anemic. I have no symptoms; just high platelets. Friday, I have corneal surgery at Hopkins and I am off baby aspirin, then off HU during recovery. I am nervous about being off the meds. Last year I was nervous being on the meds. Trying to stay calm and live my best life at 71 with 5 wonderful, young grandchildren. My best to all!
Karla