The loss of the Y chromosome in males is a hot topic among geneticist. Why is it happening in males as they age and does it have any relationship to the increased incidence of cancer and heart disease in males versus females? Google: “Y loss and implications for Oncology”In my case, LOY (loss of Y chromosome) being only 20% of plasma cells tested from BMB, without clonal expansion suggests old age phenomenon. The good is now I have a baseline that can be monitored if my MGUS labs go up.
My road to MGUS started out with an echocardiogram showing the asymmetrical, hypertrophic heart wall. Then when the blood lab showed IgG lambda 0.99 g/dl and other oral history issues (neuropathy, tendon issues, etc) amyloidosis became the main concern. Thus the battery of tests.
MGUS for me is, “well this is interesting, I wonder where this will take me?” I will track it closely and plan to live life to the fullest. My next step is to explore if I have MGNS, Monoclonal Gammopathy of Neurological Significance. The reasoning being is the neuropathy, slight balance issues, and the “weird in the head” feeling. I am trying to change my diet and started the turmeric.
Any help in how to control the nighttime/evening munchies after dinner would be greatly appreciated.
Thanks!