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What are most common side effects when starting HU (Hydroxyurea)?
Blood Cancers & Disorders | Last Active: 1 day ago | Replies (113)Comment receiving replies
My reading seems to indicate that this mutation takes a long time to develop into enough stem cells to generate enough blood cells to cause problems. We've likely had our mutations for decades before we ever see an adverse effects.
In my case, my RBC was trending up for years before it crossed the threshold to go see a specialist.
Replies to "My reading seems to indicate that this mutation takes a long time to develop into enough..."
My hematologist told me it takes about 10 yrs. before any thing starts showing. This means that mine started when I was in my mid 30s. I started noticing symptoms about 45 but chaulked them up to menopause starting. I got my official diagnosis when I was 47 but I hadn't had any labs drawn for several years so who knows when my levels actually started rising. I'm 48 now & they seem steady in the 600 -700 range without any medication help besides baby Aspirin.
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There may be some truth in your comments that humans have anomalies lurking in our bodies that take decades to emerge. That being said, these anomalies create havoc due to some event that triggers them. Medical science is very good at fixing the “now”, but miss the mark on the “how”. All so called random occurrences have a trigger. We just don’t know all the answers.