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My diagnosis is in. Negative for amyloidosis. A hypertrophic, asymmetrical heart wall septum, plus a slightly thickened heart wall, with a Mspike of 0.99g/dl of IgG lambda was the original concern for amyloidosis. Nuclear heart scan (PYP), PET scan, abdominal (fat pad) biopsy were all negative for amyloidosis.
Diagnosis is MGUS. My bone marrow biospy showed a 5.3% plasma cell count.
Treatment: repeat labs in 6 months.
Interesting note: They did a chromosome analysis on the abnormal plasma cells. Four of the 20 (20%) showed a loss of the Y chromosome. This can be old age related in males (I am 66, year old male) and it also can be a marker for other bad things at a higher percentage.
Have any other males out there on this forum with MGUS seen this if cytogenetic testing of a bone marrow biopsy was done?
Replies to "My diagnosis is in. Negative for amyloidosis. A hypertrophic, asymmetrical heart wall septum, plus a slightly..."
Hi, I had a bone marrow test done to determine if I too had MGUS. The bloodwork had already determined that much. My plasma count was at 5.0%. I am 57y/o.
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@buckett
“Have any other males out there on this forum with MGUS seen this if cytogenetic testing of a bone marrow biopsy was done?”
Can’t help you there, but I’m struck by all the information you received. It’s a lot to process. Good news on the amyloidosis.
Do you believe that you have all the information you need about MGUS? I’ll poke around the posts and see if I can identify some folks that might be able to address the cytogenetic testing of their bone marrow biopsy.