As a retired nurse, I remember a comment from a doctor who was speaking to young nursing students about medication. I was one of those students. I'll never forget what he said. "All medication have side-effects." Today,In the fifteen minutes doctors spend with patients, they rarely, if ever warn patients what negative effects to look for. It always best to search on line to find what untoward symptoms indicate potential harm to other organ. Then you take that information to your doctor. Don't be surprised if they "throw cold water" on what the internet reveals.