I have found that the liquid methotrexate works very well for me. If you don’t mind injecting yourself once a week.

“Shots work better for some people, especially if you forget to take your pills on schedule or if the pills cause nausea. Methotrexate liquid comes in vials with a hypodermic needle or in prefilled pens with various doses.

You inject the drug under the skin on your stomach or thigh. Your doctor or nurse will show you how to do this at home. If you use a prefilled pen, you’ll stick the pen into your stomach or thigh and press on it to inject the drug. Try to give yourself your shot in a different spot each time. This will help you avoid skin reactions.” David Zelman, MD
Leucovorin may reduce the effects of methotrexate
Leucovorin may reduce the effects of methotrexate. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications.