1. < Depression & Anxiety

What's your experience with duloxetine (US Brand Name; Cymbalta)?

Posted by d13 @d13, Jan 11, 2022

I was prescribed by my oncologist for the neuropathy in feet and hands. The chemotherapy treatments did this. This drug also states that it is used to treat depression and anxiety. As with any prescription medication, there could be side effects. And a huge list of what not to take with this drug. He also prescribed hydrocodone 5 mg, but to take half of pill four times daily for cancer pain. We’ll, when I got home and read about the Duloxetine use; one of the medications on the list was hydrocodone. I’m now waiting for a call from the oncologist office to see if I can take the Duloxetine with the hydrocodone. Can anyone at least tell me if they have ever taken this medication; Duloxetine? And any side effects?

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lonestarinitaly | @lonestarinitaly | Sep 20, 2024
In reply to @journey2013 "I have been taking Cymbalta 60 mg for years also for depression and haven't had any..." + (show)
@journey2013

I have been taking Cymbalta 60 mg for years also for depression and haven't had any side effects. I noticed the Cymbalta by itself wasn't helping 100% anymore. Dr. put me on Wellbuttrin and dropped Cymbalta to 30 mg. That didn't help either so dropped Wellbuttrin and back to 60 mg Cymbalta. Will be seeing him next week and wondering if anyone else has needed to add another depression drug to Cymbalta and what their experience was?

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Just started Cymbalta last night. Bad cramps and diarrhea. Will these stay or go away?

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grfxguru | @grfxguru | Sep 22, 2024

I switched from Wellbutrin to 60mg Duloxetine approximately 2 years ago for severe depression. I was concerned with weight gain and different side effects.
To date no significant side effects. No weight gain.
Sometimes I wonder if it’s effective, but overall I’m stable at least.

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bajjerfan | @bajjerfan | Oct 3, 2024

These days if you have questions about drug interactions you can do a "GOOGLE" search for for example Cymbalta plus/+ Hydrocodone and you should get some useful info. Talk to your pharmacist if you need more clarification. I was prescribed Baclofen when I was taking Lyrica and Tramadol and the pharmacist didn't flag it. Turned out to be a no no.
When I was recovering from adrenal and renal surgery at Mayo recently I was told to stop taking the BP meds amlodipine and Losartan. I'm not sure if that order was compliments of the Mayo pharmacy or one of the Mayo physicians. I don't miss either one and I'm doing fine without them.

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yanks950 | @yanks950 | 6 hours ago
In reply to @ess77 "@d13, and all...I've taken Cymbalta for several years with excellent results. It was first prescribed for..." + (show)
@ess77

@d13, and all...I've taken Cymbalta for several years with excellent results. It was first prescribed for help with fibromyalgia pain, peripheral neuropathy as well. It may help with depression, I hope so since that's part of the whole picture with fibromyalgia and other health issues I have. I've tapered off several other drugs with the help of my physician, at my request as I was on far too much chemical medication and was determined to reduce the stuff.

I now take 120 mg of Cymbalta. It helps my fibromyalgia and the peripheral neurology is much improved. I'm off hydrocodone, 800 mg ibuprofen 4x daily for years, Neurontin, Lyrica, and others. Now, I take Cymbalta, use medical marijuana 1:1, CBD:THC capsules and/or tincture at night, Requip for restless legs and it helps a lot with walking and daytime movement, and other meds I'll take for a long time. But, I'm off the really strong chemicals that affect the brain and cause fuzzy brain and other side effects. Now, I'm closer to my real self than I've been for as long as I can remember. It's wonderful. I feel free. And, Cymbalta is part of that free feeling. It's a good drug for me and my needs. I will continue to take it until I'm healed or ???

I hope this little testimonial from a patient with multiple health issues. Of all the drugs I've taken over the years, it helps the best at what it does and with no negatives. I have less pain and better control with the changes I've made. I send you blessings as you walk this journey through the medical system and your health challenges. Blessings, elizabeth

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I have been on 90mg for years due to anxiety and depression. I have been feeling really good up until about a month or so ago. Out of no where my anxiety came back 10 fold and I’m not sure if increasing to 120 is the right move. I am very sensitive to medicine changes. How was your increase in dosage?

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yanks950 | @yanks950 | 6 hours ago
In reply to @luv2hike "I have also been taking Cymbalta for years (15) . I take it for depression and..." + (show)
@luv2hike

I have also been taking Cymbalta for years (15) . I take it for depression and haven't noticed any side effects. It has helped me a lot, especially after trying other meds; Effexor, Paxil. I take 120mg daily. Your health condition is different from mine so it is always good to talk to your pharmacist. I hope it helps you and wish you all the best!

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Did you have any side effects increasing to 120?

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