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My new nephrologist wants to decrease my Tacrolimus dose.
Kidney & Bladder | Last Active: Jan 20 5:46pm | Replies (9)Comment receiving replies
Hello All
I have been recommended to keep the Tacrolimus levels between 4 - 6, which in my case will cause reduction in Tacrolimus dosage From 3x.5mg to 2x.5 mg ( after 5 years of Transplant) as I have had some body weight loss.
Question in my mind after reducing Tacrolimus the WBC count will rise ...can someone share their experience on how high did the WBC count rise. Reason is high WBC count can cause an adverse impact on the Transplanted Kidney.
Thanks
Replies to "Hello All I have been recommended to keep the Tacrolimus levels between 4 - 6, which..."
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@l0lag0lag0b3 - I have not experienced any elevation in my WBC count when my Tacrolimus dosage has been reduced. And, over time my trough level goal has been reduced from what was my during my earlier post transplant years. I am approaching 16 years post liver and kidney transplant, and I think that my current recommended Tac trough goal is same as
yours.
To answer your question about possible raised WBC - My WBC level has remained consistent over the years, and has not been affected when my Tacrolimus dosage has been reduced. However, I want to add theat whenever my Tacrolimus dosage has been reduced, it has been at only with 0.5 mg daily reduction. And my labs are repeated within 2 weeks to be sure that my liver and kidney are not adversely affected!
BTW - My experience is that it is okay for the tacrolimus level out of the specified range because of our individual reactions and health conditions. My transplant team looks at pattern over time alongside my overall health and lab results.
I hope that you have success with lowering the Tacrolimus if that is what your kidney doctor recommends. Is your transplant team involved? How will any change in medication be monitored?